GPCR-I-TASSER model for Q6NWR6
(Q6NWR6_HUMAN GPR68 protein (Fragment) OS=Homo sapiens GN=GPR68 PE=2 SV=1)
GPCR Sequence:
>tr|Q6NWR6|Q6NWR6_HUMAN GPR68 protein (Fragment) OS=Homo sapiens GN=GPR68 PE=2 SV=1
MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLPLYFGYLQIKARNELGVYL
CNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRY
LAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQA
WQRAINYYRFLVGFLFPICLLLASYQGILRAVRRGHGTQKSRKDQIQRLVLSTVVIFLAC
FLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARL
RGACLAFLTCSRTGRAREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNSPGSGGFP
TGRLA
Estimation of the GPCR-I-TASSER model for Q6NWR6
C-score = 0.280
TM-score = 0.750 (estimated)
RMSD = 6.0 A (estimated)
Here, C-score is a confidence score of the GPCR-I-TASSER predictions which
is typically in [-5,2]. TM-score and RMSD measure how close the
model is to the native structure and both are estimated based
on the C-score. TM-score is in [0,1] with a value >0.5 implying
the model of correct topology. The TM-score and RMSD estimations
are made only for the first model because absolute values of
TM-score and RMSD for the lower-rank models do not strongly
correlate with the C-score. The models are ranked based on the
structure density of GPCR-I-TASSER simulations.
The top ten threading templates used by GPCR-I-TASSER
Reference:
J Zhang, J Yang, R Jang, Y Zhang, Novel hybrid approach to G protein-coupled receptor structure modeling and case study on human genome, submitted, 2014.
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