GPCR-I-TASSER model for O14626
(GP171_HUMAN Probable G-protein coupled receptor 171 OS=Homo sapiens GN=GPR171 PE=2 SV=1)
GPCR Sequence:
>sp|O14626|GP171_HUMAN Probable G-protein coupled receptor 171 OS=Homo sapiens GN=GPR171 PE=2 SV=1
MTNSSFFCPVYKDLEPFTYFFYLVFLVGIIGSCFATWAFIQKNTNHRCVSIYLINLLTAD
FLLTLALPVKIVVDLGVAPWKLKIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLTHSC
KIYRIQEPGFAKMISTVVWLMVLLIMVPNMMIPIKDIKEKSNVGCMEFKKEFGRNWHLLT
NFICVAIFLNFSAIILISNCLVIRQLYRNKDNENYPNVKKALINILLVTTGYIICFVPYH
IVRIPYTLSQTEVITDCSTRISLFKAKEATLLLAVSNLCFDPILYYHLSKAFRSKVTETF
ASPKETKAQKEKLRCENNA
Estimation of the GPCR-I-TASSER model for O14626
C-score = 1.010
TM-score = 0.850 (estimated)
RMSD = 4.2 A (estimated)
Here, C-score is a confidence score of the GPCR-I-TASSER predictions which
is typically in [-5,2]. TM-score and RMSD measure how close the
model is to the native structure and both are estimated based
on the C-score. TM-score is in [0,1] with a value >0.5 implying
the model of correct topology. The TM-score and RMSD estimations
are made only for the first model because absolute values of
TM-score and RMSD for the lower-rank models do not strongly
correlate with the C-score. The models are ranked based on the
structure density of GPCR-I-TASSER simulations.
The top ten threading templates used by GPCR-I-TASSER
Reference:
J Zhang, J Yang, R Jang, Y Zhang, Novel hybrid approach to G protein-coupled receptor structure modeling and case study on human genome, submitted, 2014.
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