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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	FF33NL9U5G
Molecular formula	C29H32N6OS
IUPAC name	2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone
Molecular weight	512.676
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.4
Synonyms	Ethanone, 1-(2-((1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl)-2,7-diazaspiro(3.5)non-7-yl)-2-(2-methylimidazo(2,1-b)thiazol-6-yl)- SB16996 AKOS034831614 HY-12584 ZINC72317087 1334782-79-4 CHEMBL3287218 PF-05190457, >=95% (HPLC) 7-[(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)acetyl]-2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonane SCHEMBL2445443 (R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone BDBM50019926 PF 05190457 ZIUDADZJCKGWKR-AREMUKBSSA-N 2-(2-methylimidazo[2,1-b][1,3]thiazol-6-yl)-1-[2-[(1R)-5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]-2,7-diazaspiro[3.5]nonan-7-yl]ethanone CS-0012053 PF-5190457 GTPL9060 UNII-FF33NL9U5G 1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone PF-05190457 [ Show all ]
Inchi Key	ZIUDADZJCKGWKR-AREMUKBSSA-N
Inchi ID	InChI=1S/C29H32N6OS/c1-19-11-25(31-18-30-19)22-3-5-24-21(12-22)4-6-26(24)35-16-29(17-35)7-9-33(10-8-29)27(36)13-23-15-34-14-20(2)37-28(34)32-23/h3,5,11-12,14-15,18,26H,4,6-10,13,16-17H2,1-2H3/t26-/m1/s1
PubChem CID	58438464
ChEMBL	CHEMBL3287218
IUPHAR	9060
BindingDB	50019926
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
429579	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
429578	Growth hormone secretagogue receptor type 1	Q92847	GHSR	Homo sapiens (Human)	366
555419	Growth hormone secretagogue receptor type 1	O08725	Ghsr	Rattus norvegicus (Rat)	364
555420	Growth hormone secretagogue receptor type 1	Q99P50	Ghsr	Mus musculus (Mouse)	364
429580	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466

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