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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15933
Molecular formula	C30H30N4O3
IUPAC name	4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-N-(1'-methylspiro[2H-1-benzofuran-3,4'-piperidine]-5-yl)benzamide
Molecular weight	494.595
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.4
Synonyms	N-[1'-Methylspiro[benzofuran-3(2H),4'-piperidine]-5-yl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazole-3-yl)-1,1'-biphenyl-4-carboxamide BDBM50086096 L014628 2''-Methyl-4''-(5-methyl-[1,2,4]oxadiazol-3-yl)-biphenyl-4-carboxylic acid [2,3-Dihydro-1''-methylspiro(benzofuran-3,4''-piperidine)]-amide SCHEMBL7164497 N-(2,3-Dihydro-1''-methylspiro[benzofuran-3,4''-piperidine]-5-yl)-2''-methyl-4''-(5-methyl-1,2,4-oxadiazol-3-yl)biphenylcarboxamide [ Show all ]
Inchi Key	XNFJKHWCJLRFLZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H30N4O3/c1-19-16-23(28-31-20(2)37-33-28)8-10-25(19)21-4-6-22(7-5-21)29(35)32-24-9-11-27-26(17-24)30(18-36-27)12-14-34(3)15-13-30/h4-11,16-17H,12-15,18H2,1-3H3,(H,32,35)
PubChem CID	10838923
ChEMBL	CHEMBL15933
IUPHAR	N/A
BindingDB	50086096
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
396257	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
396252	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
396253	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
396254	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
396255	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
396256	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471

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