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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL386823
Molecular formula	C57H91N17O12
IUPAC name	(2S)-1-[(2S)-4-amino-2-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-4-oxobutanoyl]-N-[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Molecular weight	1206.46
Hydrogen bond acceptor	15
Hydrogen bond donor	16
XlogP	-0.6
Synonyms	BDBM85376 (Pro30,tyr32,leu34)-neuropeptide y(28-36) NPY 28-36, [P30, Y32, L34] BW-1911U90 161650-01-7 Ile-Asn-Pro-Ile-Tyr-Arg-Leu-Arg-Tyr-NH2 BDBM50034121 NPY mod28-36, porcine NCGC00167264-01 [ Show all ]
Inchi Key	XLONJGQDWUWWLC-ZXCMXKESSA-N
Inchi ID	InChI=1S/C57H91N17O12/c1-7-31(5)45(59)53(84)72-42(29-44(58)77)55(86)74-25-11-14-43(74)52(83)73-46(32(6)8-2)54(85)71-41(28-34-17-21-36(76)22-18-34)51(82)68-38(13-10-24-66-57(63)64)49(80)70-40(26-30(3)4)50(81)67-37(12-9-23-65-56(61)62)48(79)69-39(47(60)78)27-33-15-19-35(75)20-16-33/h15-22,30-32,37-43,45-46,75-76H,7-14,23-29,59H2,1-6H3,(H2,58,77)(H2,60,78)(H,67,81)(H,68,82)(H,69,79)(H,70,80)(H,71,85)(H,72,84)(H,73,83)(H4,61,62,65)(H4,63,64,66)/t31-,32-,37-,38-,39-,40-,41-,42-,43-,45-,46-/m0/s1
PubChem CID	10418848
ChEMBL	CHEMBL386823
IUPHAR	N/A
BindingDB	85376, 50034121
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
395056	Neuropeptide Y receptor type 1	P21555	Npy1r	Rattus norvegicus (Rat)	382
395057	Neuropeptide Y receptor type 1	Q9WVD0	NPY1R	Cavia porcellus (Guinea pig)	383
395058	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
395060	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
395062	Neuropeptide Y receptor type 2	Q9Z2D5	NPY2R	Cavia porcellus (Guinea pig)	381
395061	Neuropeptide Y receptor type 4	P50391	NPY4R	Homo sapiens (Human)	375
395059	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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