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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Telenzepine
Molecular formula	C19H22N4O2S
IUPAC name	1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one
Molecular weight	370.471
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.7
Synonyms	SPBio_002485 Telenzepino [Spanish] 1-methyl-10-[2-(4-methylpiperazin-1-yl)acetyl]-5H-thieno[3,4-b][1,5]benzodiazepin-4-one VSWPGAIWKHPTKX-UHFFFAOYSA-N BRD-K06147391-300-04-3 CCG-205278 DSSTox_GSID_45209 L001013 NCGC00015987-04 NSC_5387 Telenzepine dihydrochloide Tocris-1122 4,9-Dihydro-3-methyl-4-((4-methyl-1-piperazinyl)acetyl)-10H-thieno(3,4-b)(1,5)benzodiazepin-10-one API0015667 BY-802 CHEMBL253978 GTPL8594 LS-177594 NCGC00015987-07 Prestwick2_000303 Telenzepine [INN] Tox21_110274_1 4,9-Dihydro-3-methyl-4beta-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one BRD-K06147391-003-01-9 CAS-80880-90-6 D0FX4J HMS3374A10 NCGC00015987-02 NCGC00025013-02 SCHEMBL49345 Spectrum3_001839 Telenzepinum 3-methyl-4-(2-(4-methylpiperazin-1-yl)acetyl)-4H-benzo[b]thieno[3,4-e][1,4]diazepin-10(9H)-one ZINC19796161 BSPBio_000266 CHEBI:92110 DSSTox_RID_80752 Lopac-T-122 NCGC00015987-05 Prestwick0_000303 Telenzepine dihydrochloride hydrate (+)-Telenzepine Tox21 110274 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride BDBM82376 C19H22N4O2S CTK6I3128 HMS2089M03 MLS000069348 NCGC00015987-09 Prestwick3_000303 SMR000058848 Telenzepino 0990EG3K10 UNII-0990EG3K10 80880-90-6 BRD-K06147391-300-03-5 CAS_80880-90-6 DSSTox_CID_25209 KBio3_003022 NCGC00015987-03 NCGC00025013-03 Telenzepinum [Latin] 3-methyl-4-[(4-methylpiperazin-1-yl)acetyl]-4,9-dihydro-10h-thieno[3,4-b][1,5]benzodiazepin-10-one [3H](+)telenzepine AC1L1K8Q BSPBio_003517 DTXSID5045209 Lopac0_001204 NCGC00015987-06 Prestwick1_000303 Telenzepine hydrochloride (-)-Telenzepine Tox21_110274 4,9-Dihydro-3-methyl-4alpha-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one BPBio1_000294 CAS-147416-96-4 D08XDK HMS2235P06 NCGC00015987-01 NCGC00025013-01 SBI-0051171.P002 [ Show all ]
Inchi Key	VSWPGAIWKHPTKX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22N4O2S/c1-13-18-14(12-26-13)19(25)20-15-5-3-4-6-16(15)23(18)17(24)11-22-9-7-21(2)8-10-22/h3-6,12H,7-11H2,1-2H3,(H,20,25)
PubChem CID	5387
ChEMBL	CHEMBL253978
IUPHAR	8594
BindingDB	82376
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
363454	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
363448	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
363449	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
363451	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
363452	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478
363453	Muscarinic acetylcholine receptor M4	P41986	CHRM4	Bos taurus (Bovine)	126
363455	Muscarinic acetylcholine receptor M4	P17200	CHRM4	Gallus gallus (Chicken)	490
363450	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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