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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	RF 9
Molecular formula	C26H38N6O3
IUPAC name	N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]adamantane-1-carboxamide
Molecular weight	482.629
Hydrogen bond acceptor	4
Hydrogen bond donor	5
XlogP	1.4
Synonyms	SCHEMBL18041259 Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butyl]-amide D08UWO 1-adamantanecarbonyl-Arg-Phe-NH2 BDBM50336912 MolPort-023-276-894 CHEMBL1672380 ZINC43102258 AKOS024457741 GTPL1486 N(2)-(tricyclo[3.3.1.1(3,7)]decan-1-ylcarbonyl)-L-arginyl-L-phenylalaninamide 1-Adamantanecarbonyl-RF-NH2 CHEBI:140980 RF9 876310-60-0 CS-7903 B7463 HY-107382 NCGC00485847-01 [ Show all ]
Inchi Key	UMKHUSRDQFQHAK-RNJMTYCLSA-N
Inchi ID	InChI=1S/C26H38N6O3/c27-22(33)21(12-16-5-2-1-3-6-16)31-23(34)20(7-4-8-30-25(28)29)32-24(35)26-13-17-9-18(14-26)11-19(10-17)15-26/h1-3,5-6,17-21H,4,7-15H2,(H2,27,33)(H,31,34)(H,32,35)(H4,28,29,30)/t17?,18?,19?,20-,21-,26?/m0/s1
PubChem CID	53320361
ChEMBL	CHEMBL1672380
IUPHAR	1486
BindingDB	50336912
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
340270	KiSS-1 receptor	Q969F8	KISS1R	Homo sapiens (Human)	398
455205	Mas-related G-protein coupled receptor member X1	Q8R4G1	Mrgprx1	Rattus norvegicus (Rat)	323
455206	Mas-related G-protein coupled receptor member X1	Q8CIP3	Mrgprx1	Mus musculus (Mouse)	322
455207	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322
340269	Neuropeptide FF receptor 1	Q9GZQ6	NPFFR1	Homo sapiens (Human)	430
340271	Neuropeptide FF receptor 2	Q9Y5X5	NPFFR2	Homo sapiens (Human)	522

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