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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL270026
Molecular formula	C27H31NO3
IUPAC name	4-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]-2-(2-methylpropyl)benzoic acid
Molecular weight	417.549
Hydrogen bond acceptor	4
Hydrogen bond donor	3
XlogP	3.1
Synonyms	(R)-4''-(2-(2-hydroxy-2-phenylethylamino)ethyl)-3-isobutylbiphenyl-4-carboxylic acid 4''-[2-((R)-2-Hydroxy-2-phenyl-ethylamino)-ethyl]-3-isobutyl-biphenyl-4-carboxylic acid BDBM50236181 SCHEMBL5668838 4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)-10-isobutyl-4-biphenylcarboxylic acid
Inchi Key	NCTDWZFQXDIUEY-SANMLTNESA-N
Inchi ID	InChI=1S/C27H31NO3/c1-19(2)16-24-17-23(12-13-25(24)27(30)31)21-10-8-20(9-11-21)14-15-28-18-26(29)22-6-4-3-5-7-22/h3-13,17,19,26,28-29H,14-16,18H2,1-2H3,(H,30,31)/t26-/m0/s1
PubChem CID	10002049
ChEMBL	CHEMBL270026
IUPHAR	N/A
BindingDB	50236181
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
220158	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
220159	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
220156	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
220157	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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