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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MGS-0039
Molecular formula	C15H14Cl2FNO5
IUPAC name	(1R,2R,3R,5R,6R)-2-amino-3-[(3,4-dichlorophenyl)methoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	378.177
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	-0.7
Synonyms	(1R,2R,3R,5R,6R)-2-amino-3-[(3,4-dichlorophenyl)methoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid D0S9VL SCHEMBL234576 569686-87-9 GTPL1397 (1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid D0T3DG (1R, 2R, 3R, 5R, 6R)-2-amino-3-(3,4-dichlorobenzyloxy)-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid BCI-632 LFAGGDAZZKUVKO-JAGWWQSPSA-N (1r,2r,3r,5r,6r)-2-amino-3-(3,4-dichlorobenzyloxy)6-fluorobicyclo[3.1.0] hexane-2,6-dicarboxylic acid CHEMBL186453 MGS0039 DTXSID40432407 (1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichloro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid BDBM50151435 MGS 0039 [ Show all ]
Inchi Key	LFAGGDAZZKUVKO-JAGWWQSPSA-N
Inchi ID	InChI=1S/C15H14Cl2FNO5/c16-8-2-1-6(3-9(8)17)5-24-10-4-7-11(14(7,18)12(20)21)15(10,19)13(22)23/h1-3,7,10-11H,4-5,19H2,(H,20,21)(H,22,23)/t7-,10-,11+,14-,15+/m1/s1
PubChem CID	9886034
ChEMBL	CHEMBL186453
IUPHAR	1397
BindingDB	50151435
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
185816	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
185817	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
185819	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
185811	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
185815	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
185814	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
185813	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
185812	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
185818	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915

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