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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL83255
Molecular formula	C20H24FN3OS
IUPAC name	1-[4-[[(13-fluoro-5-thia-3-azatricyclo[8.4.0.02,6]tetradeca-1(10),2(6),3,11,13-pentaen-4-yl)amino]methyl]piperidin-1-yl]ethanone
Molecular weight	373.49
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.0
Synonyms	BDBM50145239 SCHEMBL7997165 1-{4-[(9-Fluoro-5,6-dihydro-4H-3-thia-1-aza-benzo[e]azulen-2-ylamino)-methyl]-piperidin-1-yl}-ethanone
Inchi Key	GMCCBRBEVQXKMD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H24FN3OS/c1-13(25)24-9-7-14(8-10-24)12-22-20-23-19-17-11-16(21)6-5-15(17)3-2-4-18(19)26-20/h5-6,11,14H,2-4,7-10,12H2,1H3,(H,22,23)
PubChem CID	9799669
ChEMBL	CHEMBL83255
IUPHAR	N/A
BindingDB	50145239
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
99775	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
99776	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
99777	Neuropeptide Y receptor type 4	P50391	NPY4R	Homo sapiens (Human)	375
99774	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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