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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL603690
Molecular formula	C24H22F3NO3S
IUPAC name	4-[(1S)-1-[[2,5-dimethyl-4-[[4-(trifluoromethyl)phenyl]methyl]thiophene-3-carbonyl]amino]ethyl]benzoic acid
Molecular weight	461.499
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	5.9
Synonyms	SCHEMBL2353056 4-{(1S)-1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}-carbonyl)amino]ethyl}benzoic acid BDBM50308129 DOTIWNYTQPDMBR-ZDUSSCGKSA-N 4-{(1S)-1-[({2,5-dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]ethyl}benzoic acid
Inchi Key	DOTIWNYTQPDMBR-ZDUSSCGKSA-N
Inchi ID	InChI=1S/C24H22F3NO3S/c1-13(17-6-8-18(9-7-17)23(30)31)28-22(29)21-15(3)32-14(2)20(21)12-16-4-10-19(11-5-16)24(25,26)27/h4-11,13H,12H2,1-3H3,(H,28,29)(H,30,31)/t13-/m0/s1
PubChem CID	24952927
ChEMBL	CHEMBL603690
IUPHAR	N/A
BindingDB	50308129
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
65309	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
65313	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
65315	Prostaglandin D2 receptor 2	Q9Y5Y4	PTGDR2	Homo sapiens (Human)	395
65317	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
65310	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
65314	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
65316	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
65311	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
65312	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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