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Ligand

NameCHEMBL3746457
Molecular formulaC18H15FN4O2
IUPAC name5-(5-fluoropyridin-2-yl)-2-(phenoxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight338.342
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP2.2
SynonymsBDBM50134443
CNYVJDHTGDPUBS-UHFFFAOYSA-N
5-(5-fluoropyridin-2-yl)-2-(phenoxymethyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one
SCHEMBL9938477
Inchi KeyCNYVJDHTGDPUBS-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H15FN4O2/c19-13-6-7-17(20-11-13)22-8-9-23-16(18(22)24)10-14(21-23)12-25-15-4-2-1-3-5-15/h1-7,10-11H,8-9,12H2
PubChem CID67974411
ChEMBLCHEMBL3746457
IUPHARN/A
BindingDB50134443
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
522872Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
522871Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
522870Metabotropic glutamate receptor 3Q14832GRM3Homo sapiens (Human)879
522876Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
522869Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
522874Metabotropic glutamate receptor 6P35349Grm6Rattus norvegicus (Rat)871
522873Metabotropic glutamate receptor 7Q14831GRM7Homo sapiens (Human)915
522877Metabotropic glutamate receptor 8O00222GRM8Homo sapiens (Human)908
522875Platelet-activating factor receptorP25105PTAFRHomo sapiens (Human)342

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