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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL81486
Molecular formula	C24H28ClN5O2
IUPAC name	4-[2-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]ethylamino]-2-methyl-6-phenylpyridazin-3-one
Molecular weight	453.971
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.9
Synonyms	6-Phenyl-4-[2-[4-(5-chloro-2-methoxyphenyl)piperazino]ethylamino]-2-methylpyridazine-3(2H)-one 4-{2-[4-(5-Chloro-2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-2-methyl-6-phenyl-2H-pyridazin-3-one BDBM50101658
Inchi Key	BJGCUGXZSIBUBN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H28ClN5O2/c1-28-24(31)21(17-20(27-28)18-6-4-3-5-7-18)26-10-11-29-12-14-30(15-13-29)22-16-19(25)8-9-23(22)32-2/h3-9,16-17,26H,10-15H2,1-2H3
PubChem CID	10928520
ChEMBL	CHEMBL81486
IUPHAR	N/A
BindingDB	50101658
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25057	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
25059	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
25060	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
25058	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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