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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL517244
Molecular formula	C35H44N2O
IUPAC name	N-methyl-N-[[4-(3-piperidin-1-ylpropoxy)phenyl]methyl]-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine
Molecular weight	508.75
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	7.8
Synonyms	N/A
Inchi Key	AQQFXOLTZFTABW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C35H44N2O/c1-36(27-28-15-17-29(18-16-28)38-26-10-25-37-23-7-2-8-24-37)22-9-20-35-21-19-30(31-11-3-5-13-33(31)35)32-12-4-6-14-34(32)35/h3-6,11-18,30H,2,7-10,19-27H2,1H3
PubChem CID	25212276
ChEMBL	CHEMBL517244
IUPHAR	N/A
BindingDB	50277046
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12018	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
12022	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
12023	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
12020	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
12019	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
12021	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445

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