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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1O8PYY
Molecular formula	C17H25ClN2O3
IUPAC name	5-chloro-3-ethyl-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide
Molecular weight	340.848
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.1
Synonyms	AB01563230_01 SPBio_003033 L000754 Prestwick2_000932 Prestwick0_000932 5-chloro-3-ethyl-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-hydroxy-6-methoxybenzamide SCHEMBL572122 BRD-A05994177-003-02-5 Prestwick1_000932 [ Show all ]
Inchi Key	AADCDMQTJNYOSS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H25ClN2O3/c1-4-11-9-13(18)16(23-3)14(15(11)21)17(22)19-10-12-7-6-8-20(12)5-2/h9,12,21H,4-8,10H2,1-3H3,(H,19,22)
PubChem CID	6713986
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
98	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
97	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
99	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
96	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
95	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
94	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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