Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

You can:

Check the GPCR table for details.
Go to the ligand list to see ligands that interacts with this GPCR.
Go to the individual ligand page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

GPCR

Name	Uracil nucleotide/cysteinyl leukotriene receptor
Species	Homo sapiens (Human)
Gene	GPR17
Synonym	GPR17 P2Y-like receptor G-protein coupled receptor 17 R12 UDP/CysLT receptor uracil nucleotide/cysteinyl leukotriene receptor [ Show all ]
Disease	N/A
Length	367
Amino acid sequence	MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGPPPSFEGKTNESSLSAKSEL
UniProt	Q13304
Protein Data Bank	N/A
GPCR-HGmod model	Q13304
3D structure model	This predicted structure model is from GPCR-EXP Q13304.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL1075162
IUPHAR	88
DrugBank	N/A

Known ligands

You can:

Click GLASS IDs to check the association information.
Click ligand names to check details of the ligands.
Download a TSV version of all interaction information.
Download a SDF structure collection of all known ligands.

GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
38817	CHEMBL129841	C11H17N5O9P2	425.231	13 / 5	-2.9	No
47065	CID 11954340	C17H21Cl2F3N5Na4O12P3S2	864.274	21 / 3	N/A	No
49668	SCHEMBL9186131	C12H10BrNO4	312.119	4 / 3	2.4	Yes
71529	CHEMBL1098419	C12H18ClN4O13P3	554.662	16 / 7	-3.8	No
75224	CHEMBL1094760	C10H14ClN5O9P2	445.646	13 / 5	-2.0	No
91841	2'-Deoxy-N6-methyl adenosine 3',5'-diphosphate diammonium salt	C11H23N7O9P2	459.293	13 / 5	N/A	No
538321	CHEMBL3968577	C18H15NO4	309.321	4 / 3	3.3	Yes
94846	Uridine-5'-diphosphate sodium salt(1:3)	C9H11N2Na3O12P2	470.106	12 / 3	N/A	No
553785	leukotriene C4	C30H47N3O9S	625.778	11 / 7	0.7	No
553859	ASN 04885796	C28H28FN5O4	517.561	7 / 1	3.8	No
118210	CHEMBL1096742	C15H36N9O13P3	643.424	21 / 11	N/A	No
553897	Udp galactose	C15H24N2O17P2	566.302	17 / 9	-6.3	No
553899	UDP-glucose	C15H24N2O17P2	566.302	17 / 9	-6.3	No
144934	SCHEMBL9186177	C12H10BrNO4	312.119	4 / 3	2.4	Yes
539901	CHEMBL53914	C12H9F2NO4	269.204	6 / 3	1.9	Yes
554030	ASN 04421891	C30H32N6O3	524.625	7 / 1	3.8	No
554126	ASN 02563583	C25H24N4O3S	460.552	6 / 1	4.8	Yes
173234	Mdl-29951	C12H9Cl2NO4	302.107	4 / 3	2.9	Yes
173235	CHEMBL3264006	C12H9Cl2NO4	310.139	4 / 3	2.9	Yes
184186	CHEMBL1094109	C11H18N5O13P3	521.208	17 / 7	-5.0	No
540952	CHEMBL3897541	C14H15NO4	261.277	4 / 3	2.4	Yes
215890	CHEMBL3132880	C12H9Br2NO4	391.015	4 / 3	3.0	Yes
219390	Pranlukast	C27H23N5O4	481.512	7 / 2	4.2	Yes
229594	CHEMBL1097652	C18H20N5O13P3	607.301	17 / 7	-3.7	No
237594	CHEMBL3132881	C12H9I2NO4	485.016	4 / 3	3.0	Yes
246413	CHEMBL1094760	C10H20ClN7O9P2	479.708	15 / 7	N/A	No
254257	CHEMBL3132886	C12H10INO4	359.119	4 / 3	2.3	Yes
254640	CHEMBL1097279	C17H21Cl2F3N5O12P3S2-4	772.314	21 / 3	-1.3	No
273927	CHEMBL3132882	C14H9F6NO4	369.219	10 / 3	3.4	Yes
275412	CHEMBL50976	C14H15NO6	293.275	6 / 3	1.6	Yes
288829	CHEMBL1094109	C11H30N9O13P3	589.332	21 / 11	N/A	No
302604	CHEMBL1094759	C9H22IN5O12P2	581.15	15 / 9	N/A	No
307182	CHEMBL1096742	C15H24N5O13P3	575.3	17 / 7	-3.8	No
567224	ASN 06917370	C24H21ClF3N7O2	531.924	8 / 2	3.6	No
544661	CHEMBL3915176	C24H19NO4	385.419	4 / 3	4.9	Yes
327445	CHEMBL590494	C9H13IN2O12P2	530.057	12 / 6	-4.4	No
554903	ASN 04450772	C26H25N5O6S	535.575	9 / 4	2.6	No
333305	montelukast	C35H36ClNO3S	586.187	5 / 2	7.7	No
336631	CHEMBL3132883	C12H8Cl2FNO4	320.097	5 / 3	3.0	Yes
365168	CHEMBL1098419	C12H30ClN8O13P3	622.786	20 / 11	N/A	No
382382	CHEMBL1098083	C11H29ClN9O13P3	623.774	21 / 11	N/A	No
385970	Gavestinel	C18H12Cl2N2O3	375.205	3 / 3	4.4	Yes
386045	CHEMBL1097652	C18H32N9O13P3	675.425	21 / 11	N/A	No
388135	uridine-5'-diphosphate	C9H11N2O12P2-3	401.137	12 / 3	-5.0	No
555243	Uridine 5'-diphosphate	C9H14N2O12P2	404.161	12 / 6	-4.7	No
395604	CHEMBL3132887	C12H10INO4	359.119	4 / 3	2.3	Yes
555318	leukotriene D4	C25H40N2O6S	496.663	8 / 5	1.4	Yes
547109	CHEMBL3921330	C15H13Cl2NO6	374.17	6 / 3	2.3	Yes
547341	3-(2-carboxyethyl)-6-chloro-1H-indole-2-carboxylic Acid	C12H10ClNO4	267.665	4 / 3	2.3	Yes
555426	Adenosine triphosphate	C10H16N5O13P3	507.181	17 / 7	-5.7	No
438251	CHEMBL1098083	C11H17ClN5O13P3	555.65	17 / 7	-4.1	No

zhanglab

zhanggroup.org | +65-6601-1241 | Computing 1, 13 Computing Drive, Singapore 117417