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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL445481
Molecular formula	C29H37Cl2N3O5S
IUPAC name	2-cyclohexyloxy-4-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-N-methylsulfonylbenzamide;dihydrochloride
Molecular weight	610.591
Hydrogen bond acceptor	7
Hydrogen bond donor	5
XlogP	None
Synonyms	SCHEMBL4584202
Inchi Key	ZUIRACGVBZOKRD-LPCSYZHESA-N
Inchi ID	InChI=1S/C29H35N3O5S.2ClH/c1-38(35,36)32-29(34)26-14-13-23(18-28(26)37-25-7-3-2-4-8-25)22-11-9-21(10-12-22)15-17-31-20-27(33)24-6-5-16-30-19-24;;/h5-6,9-14,16,18-19,25,27,31,33H,2-4,7-8,15,17,20H2,1H3,(H,32,34);2*1H/t27-;;/m0../s1
PubChem CID	42639492
ChEMBL	CHEMBL445481
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
437703	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
437704	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
437702	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
437705	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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