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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL445481
Molecular formula	C29H35N3O5S
IUPAC name	2-cyclohexyloxy-4-[4-[2-[[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino]ethyl]phenyl]-N-methylsulfonylbenzamide
Molecular weight	537.675
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	3.8
Synonyms	3-(Cyclohexyloxy)-4''-(2-{[(2R)-2-hydroxy-2-pyridin-3-ylethyl]amino}ethyl)-N-(methylsulfonyl)biphenyl-4-carboxamide Dihydrochloride CHEMBL1186009 BDBM50277509 SCHEMBL4585189
Inchi Key	YLQMAAMFQNYJDU-MHZLTWQESA-N
Inchi ID	InChI=1S/C29H35N3O5S/c1-38(35,36)32-29(34)26-14-13-23(18-28(26)37-25-7-3-2-4-8-25)22-11-9-21(10-12-22)15-17-31-20-27(33)24-6-5-16-30-19-24/h5-6,9-14,16,18-19,25,27,31,33H,2-4,7-8,15,17,20H2,1H3,(H,32,34)/t27-/m0/s1
PubChem CID	11272641
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50277509
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
413196	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
462728	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
413195	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
413197	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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