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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3764088
Molecular formula	C24H26N4O3
IUPAC name	N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-2-(6-oxopyridazin-1-yl)acetamide
Molecular weight	418.497
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	1.7
Synonyms	BDBM50146156 SCHEMBL11982266
Inchi Key	URLFNGRPGJRFPI-YZUZCNPQSA-N
Inchi ID	InChI=1S/C24H26N4O3/c29-22(16-28-23(30)7-4-14-25-28)27-19-10-8-17(9-11-19)15-20-12-13-21(26-20)24(31)18-5-2-1-3-6-18/h1-11,14,20-21,24,26,31H,12-13,15-16H2,(H,27,29)/t20-,21+,24+/m0/s1
PubChem CID	44472610
ChEMBL	CHEMBL3764088
IUPHAR	N/A
BindingDB	50146156
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
531158	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
531162	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
531157	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408
531159	Beta-3 adrenergic receptor	Q28524	ADRB3	Macaca mulatta (Rhesus macaque)	418
531160	Beta-3 adrenergic receptor	P26255	Adrb3	Rattus norvegicus (Rat)	400
531161	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405

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