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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL161724
Molecular formula	C21H22N4O2
IUPAC name	3-[2-[6-[2-[(2-methylpropan-2-yl)oxy]ethoxy]pyridin-3-yl]-1H-imidazol-5-yl]benzonitrile
Molecular weight	362.433
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	BDBM50123737 3-{2-[6-(2-tert-Butoxy-ethoxy)-pyridin-3-yl]-3H-imidazol-4-yl}-benzonitrile
Inchi Key	SDXRWXOUFKHXTG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22N4O2/c1-21(2,3)27-10-9-26-19-8-7-17(13-23-19)20-24-14-18(25-20)16-6-4-5-15(11-16)12-22/h4-8,11,13-14H,9-10H2,1-3H3,(H,24,25)
PubChem CID	9930778
ChEMBL	CHEMBL161724
IUPHAR	N/A
BindingDB	50123737
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
311858	Neuropeptide Y receptor type 1	P25929	NPY1R	Homo sapiens (Human)	384
311857	Neuropeptide Y receptor type 2	P49146	NPY2R	Homo sapiens (Human)	381
311856	Neuropeptide Y receptor type 5	Q63634	Npy5r	Rattus norvegicus (Rat)	445
311859	Neuropeptide Y receptor type 5	Q15761	NPY5R	Homo sapiens (Human)	445

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