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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL111685
Molecular formula	C21H29N3O2S
IUPAC name	N-[3-cyclohexyl-5-(1H-imidazol-5-yl)-5,6,7,8-tetrahydronaphthalen-1-yl]ethanesulfonamide
Molecular weight	387.542
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.6
Synonyms	SCHEMBL7097825 N-[3-cyclohexyl-5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]ethanesulfonamide QFSWDHAWKWSHQS-UHFFFAOYSA-N
Inchi Key	QFSWDHAWKWSHQS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H29N3O2S/c1-2-27(25,26)24-20-12-16(15-7-4-3-5-8-15)11-19-17(20)9-6-10-18(19)21-13-22-14-23-21/h11-15,18,24H,2-10H2,1H3,(H,22,23)
PubChem CID	10221830
ChEMBL	CHEMBL111685
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
277211	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
277210	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
277209	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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