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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL53416
Molecular formula	C22H22N4
IUPAC name	4-(4-benzylpiperazin-1-yl)pyrrolo[1,2-a]quinoxaline
Molecular weight	342.446
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.6
Synonyms	4-(4-Benzylpiperazino)pyrrolo[1,2-a]quinoxaline BDBM50408167 SCHEMBL8563750
Inchi Key	PADMFNVKWGURLR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22N4/c1-2-7-18(8-3-1)17-24-13-15-25(16-14-24)22-21-11-6-12-26(21)20-10-5-4-9-19(20)23-22/h1-12H,13-17H2
PubChem CID	10617292
ChEMBL	CHEMBL53416
IUPHAR	N/A
BindingDB	50408167
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
254626	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
254624	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
254625	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
254622	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
254623	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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