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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL65710
Molecular formula	C20H20N4S
IUPAC name	8-(4-benzylpiperazin-1-yl)-5-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaene
Molecular weight	348.468
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.6
Synonyms	BDBM50407777 S-21178 SCHEMBL7294783
Inchi Key	OYASVWZGKNBLSA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N4S/c1-2-5-16(6-3-1)15-22-10-12-23(13-11-22)19-17-7-4-9-24(17)18-8-14-25-20(18)21-19/h1-9,14H,10-13,15H2
PubChem CID	10247171
ChEMBL	CHEMBL65710
IUPHAR	N/A
BindingDB	50407777
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
253041	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
253043	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
253040	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
253042	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
253039	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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