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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Lutrepatch
Molecular formula	C60H73N15O13
IUPAC name	N-[1-[[1-[[1-[[1-[[2-[[1-[[1-[2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide
Molecular weight	1212.34
Hydrogen bond acceptor	14
Hydrogen bond donor	15
XlogP	0.5
Synonyms	Iontophoretic anti-infertility peptide (Smart Patch), Ferring/Vyteris GnRH (Lutrepatch, female fertility), Ferring GnRH (Smart Patch, female infertility), Vyteris/Ferring Luteinizing hormone releasing hormone salmon Gonadotropin-releasing hormone (Smart Patch, female infertility), Vyteris/Ferring PYR-HIS-TRP-SER-TYR-GLY-TRP-LEU-PRO-GLY-NH2 D0R9VC Iontophoretic anti-infertility peptide (Smart Patch), Vyteris/Ferring GnRH (Lutrepatch, female infertility), Ferring/Vyteris GnRH I Luteinizing hormone releasing hormone salmon, >=97% (HPLC) Anti-infertility peptide (iontophoretic/Smart Patch), Ferring/Vyteris GTPL1162 GnRH (Lutrepatch, female fertility) LH-RH (LHRH) GnRH (Smart Patch, female infertility), Ferring/Vyteris Gonadotropin-releasing hormone (Smart Patch, female infertility), Ferring/Vyteris Anti-infertility peptide (iontophoretic/Smart Patch), Vyteris/Ferring [ Show all ]
Inchi Key	NMJREATYWWNIKX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C60H73N15O13/c1-32(2)20-47(60(88)75-19-7-12-49(75)59(87)65-28-50(61)78)73-55(83)44(22-34-25-63-40-10-5-3-8-38(34)40)69-52(80)29-66-53(81)43(21-33-13-15-37(77)16-14-33)70-58(86)48(30-76)74-56(84)45(23-35-26-64-41-11-6-4-9-39(35)41)71-57(85)46(24-36-27-62-31-67-36)72-54(82)42-17-18-51(79)68-42/h3-6,8-11,13-16,25-27,31-32,42-49,63-64,76-77H,7,12,17-24,28-30H2,1-2H3,(H2,61,78)(H,62,67)(H,65,87)(H,66,81)(H,68,79)(H,69,80)(H,70,86)(H,71,85)(H,72,82)(H,73,83)(H,74,84)
PubChem CID	16132914
ChEMBL	N/A
IUPHAR	1162
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554403	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
554404	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327
554405	Gonadotropin-releasing hormone receptor	Q01776	Gnrhr	Mus musculus (Mouse)	327

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