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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL503209
Molecular formula	C25H25ClN2O5
IUPAC name	5-[[(7S)-7-[[(2R)-2-(6-chloropyridin-3-yl)-2-hydroxyethyl]amino]-5,6,7,8-tetrahydronaphthalen-2-yl]oxy]-2-methoxybenzoic acid
Molecular weight	468.934
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	1.7
Synonyms	BDBM50273079 5-[((7S)-7-{[(2R)-2-(6-Chloro-3-pyridinyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydro-2-naphthalenyl)oxy]-2-methoxybenzoic Acid
Inchi Key	MVBZNYMDBPDLIU-AVRDEDQJSA-N
Inchi ID	InChI=1S/C25H25ClN2O5/c1-32-23-8-7-20(12-21(23)25(30)31)33-19-6-3-15-2-5-18(10-17(15)11-19)27-14-22(29)16-4-9-24(26)28-13-16/h3-4,6-9,11-13,18,22,27,29H,2,5,10,14H2,1H3,(H,30,31)/t18-,22-/m0/s1
PubChem CID	24950242
ChEMBL	CHEMBL503209
IUPHAR	N/A
BindingDB	50273079
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
214881	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
214879	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
214878	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405
214880	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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