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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL62274
Molecular formula	C16H18N4S
IUPAC name	8-(4-prop-2-enylpiperazin-1-yl)-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Molecular weight	298.408
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50407785 SCHEMBL7297121 5-(4-Allyl-1-piperazinyl)pyrrolo[1,2-a]thieno[3,2-e]pyrazine
Inchi Key	MSVKSHZVXNPCBB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H18N4S/c1-2-6-18-8-10-19(11-9-18)15-14-4-3-7-20(14)16-13(17-15)5-12-21-16/h2-5,7,12H,1,6,8-11H2
PubChem CID	10590206
ChEMBL	CHEMBL62274
IUPHAR	N/A
BindingDB	50407785
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
213417	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
213414	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
213416	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
213415	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
213418	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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