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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL64727
Molecular formula	C20H18Cl2N4S
IUPAC name	8-[4-[(2,4-dichlorophenyl)methyl]piperazin-1-yl]-5-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaene
Molecular weight	417.352
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.9
Synonyms	BDBM50407791 SCHEMBL7300287
Inchi Key	MRVXWRYYLBBDQJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18Cl2N4S/c21-15-4-3-14(16(22)12-15)13-24-7-9-25(10-8-24)19-17-2-1-6-26(17)18-5-11-27-20(18)23-19/h1-6,11-12H,7-10,13H2
PubChem CID	10598044
ChEMBL	CHEMBL64727
IUPHAR	N/A
BindingDB	50407791
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
212748	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
212746	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
212745	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
212747	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
212744	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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