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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL473702
Molecular formula	C26H31N3O3
IUPAC name	4-[4-[2-[[(2R)-2-(4-aminopyridin-3-yl)-2-hydroxyethyl]amino]ethyl]phenyl]-2-(2-methylpropyl)benzoic acid
Molecular weight	433.552
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	1.9
Synonyms	BDBM50277526 (R)-4''-(2-(2-(4-aminopyridin-3-yl)-2-hydroxyethylamino)ethyl)-3-isobutylbiphenyl-4-carboxylic acid
Inchi Key	LCAAUXMMXJQKOH-VWLOTQADSA-N
Inchi ID	InChI=1S/C26H31N3O3/c1-17(2)13-21-14-20(7-8-22(21)26(31)32)19-5-3-18(4-6-19)9-11-29-16-25(30)23-15-28-12-10-24(23)27/h3-8,10,12,14-15,17,25,29-30H,9,11,13,16H2,1-2H3,(H2,27,28)(H,31,32)/t25-/m0/s1
PubChem CID	44591507
ChEMBL	CHEMBL473702
IUPHAR	N/A
BindingDB	50277526
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
183756	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
183757	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
183758	Beta-3 adrenergic receptor	O02662	ADRB3	Canis lupus familiaris (Dog)	405
183759	Beta-3 adrenergic receptor	P13945	ADRB3	Homo sapiens (Human)	408

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