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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL416662
Molecular formula	C23H21ClN4O2
IUPAC name	4-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-7-chloropyrrolo[1,2-a]quinoxaline
Molecular weight	420.897
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50408166 SCHEMBL8566070
Inchi Key	KDCOAGQKBBVYDB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21ClN4O2/c24-17-4-5-19-18(13-17)25-23(20-2-1-7-28(19)20)27-10-8-26(9-11-27)14-16-3-6-21-22(12-16)30-15-29-21/h1-7,12-13H,8-11,14-15H2
PubChem CID	19978059
ChEMBL	CHEMBL416662
IUPHAR	N/A
BindingDB	50408166
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
166261	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
166260	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
166257	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
166259	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
166258	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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