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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL300692
Molecular formula	C23H23FN4
IUPAC name	4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]-7-methylpyrrolo[1,2-a]quinoxaline
Molecular weight	374.463
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	5.1
Synonyms	BDBM50408159 SCHEMBL8567127
Inchi Key	JUSBDZIBILCYFG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H23FN4/c1-17-4-9-21-20(15-17)25-23(22-3-2-10-28(21)22)27-13-11-26(12-14-27)16-18-5-7-19(24)8-6-18/h2-10,15H,11-14,16H2,1H3
PubChem CID	10571450
ChEMBL	CHEMBL300692
IUPHAR	N/A
BindingDB	50408159
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
160442	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
160439	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
160440	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
160443	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
160441	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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