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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL40564
Molecular formula	C26H27N3O3S
IUPAC name	3-[3-(6-methoxy-1,3,3a,4,5,9b-hexahydrobenzo[e]isoindol-2-yl)propyl]-1H-[1]benzothiolo[3,2-d]pyrimidine-2,4-dione
Molecular weight	461.58
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.5
Synonyms	BDBM50087466 (Cis)3-[3-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-propyl]-1H-benzo[4,5]thieno[3,2-d]pyrimidine-2,4-dione
Inchi Key	JSVIAXKQDMQOAP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27N3O3S/c1-32-21-8-4-7-17-18(21)11-10-16-14-28(15-20(16)17)12-5-13-29-25(30)24-23(27-26(29)31)19-6-2-3-9-22(19)33-24/h2-4,6-9,16,20H,5,10-15H2,1H3,(H,27,31)
PubChem CID	44288359
ChEMBL	CHEMBL40564
IUPHAR	N/A
BindingDB	50087466
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
159107	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
159108	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
159105	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561

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