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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL389459
Molecular formula	C37H42N6O5
IUPAC name	(2S,5S,8R,12R)-5,8-dibenzyl-2-(1H-indol-3-ylmethyl)-12-morpholin-4-yl-1,4,7,10-tetrazacyclotetradecane-3,6,11,14-tetrone
Molecular weight	650.78
Hydrogen bond acceptor	6
Hydrogen bond donor	5
XlogP	3.1
Synonyms	MEN-11995
Inchi Key	JLJWVVBVFWSHGR-KYXYXWHUSA-N
Inchi ID	InChI=1S/C37H42N6O5/c44-34-22-33(43-15-17-48-18-16-43)37(47)39-24-28(19-25-9-3-1-4-10-25)40-35(45)31(20-26-11-5-2-6-12-26)42-36(46)32(41-34)21-27-23-38-30-14-8-7-13-29(27)30/h1-14,23,28,31-33,38H,15-22,24H2,(H,39,47)(H,40,45)(H,41,44)(H,42,46)/t28-,31+,32+,33-/m1/s1
PubChem CID	10326920
ChEMBL	CHEMBL389459
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
153732	Neuromedin-K receptor	P30098	TACR3	Cavia porcellus (Guinea pig)	440
153731	Substance-K receptor	P21452	TACR2	Homo sapiens (Human)	398
153733	Substance-K receptor	P79218	TACR2	Oryctolagus cuniculus (Rabbit)	384
153734	Substance-K receptor	P16610	Tacr2	Rattus norvegicus (Rat)	390
153730	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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