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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL61281
Molecular formula	C17H18N2O4
IUPAC name	(2R,4R)-4-amino-1-(naphthalen-2-ylmethyl)pyrrolidine-2,4-dicarboxylic acid
Molecular weight	314.341
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.3
Synonyms	SCHEMBL8973223 (2R,4R)-4-Amino-1-naphthalen-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid BDBM50071155
Inchi Key	IHVKGWYIKGRPEY-RHSMWYFYSA-N
Inchi ID	InChI=1S/C17H18N2O4/c18-17(16(22)23)8-14(15(20)21)19(10-17)9-11-5-6-12-3-1-2-4-13(12)7-11/h1-7,14H,8-10,18H2,(H,20,21)(H,22,23)/t14-,17-/m1/s1
PubChem CID	44302609
ChEMBL	CHEMBL61281
IUPHAR	N/A
BindingDB	50071155
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
133597	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
133592	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
133595	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
133596	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
133594	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
133593	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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