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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL456125
Molecular formula	C26H27BrN4O5
IUPAC name	N-(4-bromophenyl)-2-[4-(7-hydroxy-2,4-dioxo-1,3-dipropyl-5H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy]acetamide
Molecular weight	555.429
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.6
Synonyms	BDBM50273311 N-(4-bromophenyl)-2-(4-(7-hydroxy-2,4-dioxo-1,3-dipropyl-2,3,4,5-tetrahydro-1H-pyrrolo[3,2-d]pyrimidin-6-yl)phenoxy)acetamide
Inchi Key	IDZLUCZVCCNUTR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27BrN4O5/c1-3-13-30-23-22(25(34)31(14-4-2)26(30)35)29-21(24(23)33)16-5-11-19(12-6-16)36-15-20(32)28-18-9-7-17(27)8-10-18/h5-12,29,33H,3-4,13-15H2,1-2H3,(H,28,32)
PubChem CID	44587956
ChEMBL	CHEMBL456125
IUPHAR	N/A
BindingDB	50273311
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
130954	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
130952	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
130956	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
130953	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
130957	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
130955	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318

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