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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL172071
Molecular formula	C26H33N5O7S2
IUPAC name	N-[2-cyclopropyl-6-[2-(ethylsulfonylamino)ethoxy]-5-(2-methoxyphenoxy)pyrimidin-4-yl]-5-propan-2-ylpyridine-2-sulfonamide
Molecular weight	591.698
Hydrogen bond acceptor	12
Hydrogen bond donor	2
XlogP	3.3
Synonyms	SCHEMBL7196209 5-i-propyl-N-[6-(2-ethanesulfonylamino-ethoxy)-5-(o-methoxyphenoxy)-2-cyclopropyl-pyrimidin-4-yl]-pyridine-2-sulfonamide BDBM50124428 GWBCKOWLDKFIHO-UHFFFAOYSA-N 5-Isopropyl-pyridine-2-sulfonic acid [2-cyclopropyl-6-(2-ethanesulfonylamino-ethoxy)-5-(2-methoxy-phenoxy)-pyrimidin-4-yl]-amide N-[2-[2-Cyclopropyl-5-(2-methoxyphenoxy)6-(5-isopropyl-2-pyridinylsulfonylamino)-4-pyrimidinyloxy]ethyl]ethanesulfonamide [ Show all ]
Inchi Key	GWBCKOWLDKFIHO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H33N5O7S2/c1-5-39(32,33)28-14-15-37-26-23(38-21-9-7-6-8-20(21)36-4)25(29-24(30-26)18-10-11-18)31-40(34,35)22-13-12-19(16-27-22)17(2)3/h6-9,12-13,16-18,28H,5,10-11,14-15H2,1-4H3,(H,29,30,31)
PubChem CID	9873255
ChEMBL	CHEMBL172071
IUPHAR	N/A
BindingDB	50124428
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
106736	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
106738	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
106737	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
106739	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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