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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL149391
Molecular formula	C21H24N2O4S
IUPAC name	N-(3,4-dimethyl-1,2-oxazol-5-yl)-5-hydroxy-2-[4-(2-methylpropyl)phenyl]benzenesulfonamide
Molecular weight	400.493
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.9
Synonyms	BDBM50068730 SCHEMBL6767638 4-Hydroxy-4''-isobutyl-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Inchi Key	GTYWANZAOHNPBK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24N2O4S/c1-13(2)11-16-5-7-17(8-6-16)19-10-9-18(24)12-20(19)28(25,26)23-21-14(3)15(4)22-27-21/h5-10,12-13,23-24H,11H2,1-4H3
PubChem CID	10501166
ChEMBL	CHEMBL149391
IUPHAR	N/A
BindingDB	50068730
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
105309	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
105310	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
105311	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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