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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3633650
Molecular formula	C23H25N3O3
IUPAC name	2-[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]-1-(2-phenyl-1H-indol-3-yl)ethanone
Molecular weight	391.471
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.6
Synonyms	AKOS027324569 2-[methyl-(2-morpholin-4-yl-2-oxoethyl)amino]-1-(2-phenyl-1H-indol-3-yl)ethanone ZINC57473783 950034-18-1 BDBM50133676 MolPort-005-659-662 2-{methyl[2-(morpholin-4-yl)-2-oxoethyl]amino}-1-(2-phenyl-1H-indol-3-yl)ethan-1-one AC1PJFPF Z90240217 [ Show all ]
Inchi Key	FRUZIJBUVKTDFU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25N3O3/c1-25(16-21(28)26-11-13-29-14-12-26)15-20(27)22-18-9-5-6-10-19(18)24-23(22)17-7-3-2-4-8-17/h2-10,24H,11-16H2,1H3
PubChem CID	9044803
ChEMBL	CHEMBL3633650
IUPHAR	N/A
BindingDB	50133676
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
473502	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
473500	Extracellular calcium-sensing receptor	P48442	Casr	Rattus norvegicus (Rat)	1079
473503	G-protein coupled receptor family C group 6 member A	Q8K4Z6	Gprc6a	Mus musculus (Mouse)	928
473501	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
473504	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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