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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL63713
Molecular formula	C22H21F3N4S
IUPAC name	8-[4-[2-[2-(trifluoromethyl)phenyl]ethyl]piperazin-1-yl]-3-thia-1,7-diazatricyclo[7.3.0.02,6]dodeca-2(6),4,7,9,11-pentaene
Molecular weight	430.493
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	6.0
Synonyms	BDBM50407755
Inchi Key	FQHKGSXYDVSJCE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21F3N4S/c23-22(24,25)17-5-2-1-4-16(17)7-10-27-11-13-28(14-12-27)20-19-6-3-9-29(19)21-18(26-20)8-15-30-21/h1-6,8-9,15H,7,10-14H2
PubChem CID	10717512
ChEMBL	CHEMBL63713
IUPHAR	N/A
BindingDB	50407755
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
84687	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
84684	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
84685	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
84686	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
84688	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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