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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15139
Molecular formula	C23H29N5O3
IUPAC name	1-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-3-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]urea
Molecular weight	423.517
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	2.6
Synonyms	SCHEMBL6356822 1-[2-(5-Hydroxy-1H-indol-3-yl)-ethyl]-3-[4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-urea BDBM50086102
Inchi Key	FHMGXDNSPPUJTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29N5O3/c1-27-9-11-28(12-10-27)21-13-17(3-6-22(21)31-2)26-23(30)24-8-7-16-15-25-20-5-4-18(29)14-19(16)20/h3-6,13-15,25,29H,7-12H2,1-2H3,(H2,24,26,30)
PubChem CID	10764757
ChEMBL	CHEMBL15139
IUPHAR	N/A
BindingDB	50086102
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
78478	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
78477	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
78476	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374

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