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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Solifenacin
Molecular formula	C23H26N2O2
IUPAC name	[(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
Molecular weight	362.473
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.0
Synonyms	DB-001095 KS-00000ZV0 Solifenacin [INN:BAN] YM-67905 ((8R)-1-azabicyclo(2.2.2)octan-8-yl)(1S)-1-phenyl-3,4-dihydro-1h-isoquinoline-2-carboxylate BDBM50370682 DTXSID3048289 SB17427 Vesicare [(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate (3R)-1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate AB01565949_02 D08522 HY-A0034 YM 905 242478-37-1 AKOS015896445 NCGC00168778-01 Soliten YM-905 (+)-Solifenacin CHEBI:135530 CHEMBL1734 FBOUYBDGKBSUES-VXKWHMMOSA-N SCHEMBL188493 Vesicare (TN) [(8R)-1-azabicyclo[2.2.2]octan-8-yl] (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate 1-azabicyclo[2.2.2]oct-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate AC1L4BM3 D0L4YD I06-1893 Solifenacin (INN) YM-53705 ((8r)-1-azabicyclo(2.2.2)octan-8-yl) (1s)-1-phenyl-3,4-dihydro-1h-isoQUINOLINE-2-carboxylate BDBM50344284 DB01591 Quinuclidin-3'-yl-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylatemonosuccinate UNII-A8910SQJ1U ZINC3936683 (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl-3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate A8910SQJ1U CHEMBL1200803 CS-8096 GTPL7483 SCHEMBL9971260 Vesikur 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-,1-azabicyclo(2.2.2)oct-3-yl ester, (R-(R,S))- AJ-47452 [ Show all ]
Inchi Key	FBOUYBDGKBSUES-VXKWHMMOSA-N
Inchi ID	InChI=1S/C23H26N2O2/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19/h1-9,18,21-22H,10-16H2/t21-,22-/m0/s1
PubChem CID	154059
ChEMBL	CHEMBL1734
IUPHAR	7483
BindingDB	50370682, 50344284
DrugBank	DB01591
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
74420	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
74422	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
74419	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
74421	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
74423	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
74424	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
74425	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
74426	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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