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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL346853
Molecular formula	C20H22N2O4S
IUPAC name	N-(3,4-dimethyl-1,2-oxazol-5-yl)-2-(4-propan-2-yloxyphenyl)benzenesulfonamide
Molecular weight	386.466
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50068676 SCHEMBL6770711 4''-Isopropoxy-biphenyl-2-sulfonic acid (3,4-dimethyl-isoxazol-5-yl)-amide
Inchi Key	DYLKKVMDOFKPBE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22N2O4S/c1-13(2)25-17-11-9-16(10-12-17)18-7-5-6-8-19(18)27(23,24)22-20-14(3)15(4)21-26-20/h5-13,22H,1-4H3
PubChem CID	10620185
ChEMBL	CHEMBL346853
IUPHAR	N/A
BindingDB	50068676
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
72078	Endothelin receptor type B	P21451	Ednrb	Rattus norvegicus (Rat)	442
72077	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427
72079	Endothelin-1 receptor	P26684	Ednra	Rattus norvegicus (Rat)	426

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