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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	733750-99-7
Molecular formula	C21H24FN7O5S
IUPAC name	N-(2-fluoro-4-methylsulfonylphenyl)-5-nitro-6-[4-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]pyrimidin-4-amine
Molecular weight	505.525
Hydrogen bond acceptor	12
Hydrogen bond donor	1
XlogP	3.9
Synonyms	AR231453, >=98% (HPLC) D0R5QF NCGC00386584-02 BDBM50244791 HY-15564 UNII-07Z1P4981I 07Z1P4981I AOB87157 AR-231453 CHEMBL461384 N-(2-Fluoro-4-(methylsulfonyl)phenyl)-6-(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-5-nitropyrimidin-4-amine AX8246104 DTXSID80223614 SCHEMBL114213 (2-Fluoro-4-(methanesulfonyl)phenyl)(6-(4-(3-isopropyl-(1,2,4)oxadiazol-5-yl)piperidin-1-yl)-5-nitropyrimidin-4-yl)amine AJ-103813 C21H24FN7O5S KB-145984 ZINC40861018 1399AC AR 231453 AR231453 CS-2475 N-(2-fluoro-4-methylsulfonylphenyl)-5-nitro-6-[4-(3-propan-2-yl-1,2,4-oxadiazol-5-yl)piperidin-1-yl]pyrimidin-4-amine BCP08600 GTPL5653 SCHEMBL2734562 (2-Fluoro-4-methanesulfonyl-phenyl)-{6-[4-(3-isopropyl-[1,2,4]oxadiazol-5-yl)-piperidin-1-yl]-5-nitropyrimidin-4-yl}-amine AKOS016011527 AR-231,453 MolPort-019-939-259 4-Pyrimidinamine, N-(2-fluoro-4-(methylsulfonyl)phenyl)-6-(4-(3-(1-methylethyl)-1,2,4-oxadiazol-5-yl)-1-piperidinyl)-5-nitro- [ Show all ]
Inchi Key	DGBKNTVAKIFYNU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H24FN7O5S/c1-12(2)18-26-21(34-27-18)13-6-8-28(9-7-13)20-17(29(30)31)19(23-11-24-20)25-16-5-4-14(10-15(16)22)35(3,32)33/h4-5,10-13H,6-9H2,1-3H3,(H,23,24,25)
PubChem CID	24939268
ChEMBL	CHEMBL461384
IUPHAR	5653
BindingDB	50244791
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
59098	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335
59099	Glucose-dependent insulinotropic receptor	Q7TQN8	Gpr119	Rattus norvegicus (Rat)	468
59100	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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