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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL125588
Molecular formula	C27H22O3S
IUPAC name	2-[2-[5-(2-phenylmethoxyphenyl)thiophen-3-yl]phenyl]cyclopropane-1-carboxylic acid
Molecular weight	426.53
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.1
Synonyms	2-[2-[5-[2-(Benzyloxy)phenyl]-3-thienyl]phenyl]cyclopropane-1-carboxylic acid BDBM50134526 2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl}-cyclopropanecarboxylic acid
Inchi Key	DCYHRPUPJCRAGG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H22O3S/c28-27(29)24-15-23(24)21-11-5-4-10-20(21)19-14-26(31-17-19)22-12-6-7-13-25(22)30-16-18-8-2-1-3-9-18/h1-14,17,23-24H,15-16H2,(H,28,29)
PubChem CID	11743212
ChEMBL	CHEMBL125588
IUPHAR	N/A
BindingDB	50134526
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
56853	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
56849	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
56848	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
56847	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
56851	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
56850	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
56852	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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