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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL425681
Molecular formula	C22H34O6
IUPAC name	7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-4-phenoxybutyl]cyclopentyl]heptanoic acid
Molecular weight	394.508
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	3.2
Synonyms	7-[3,5-Dihydroxy-2-(3-hydroxy-4-phenoxy-butyl)-cyclopentyl]-heptanoic acid (15R)-9alpha,11alpha,15-Trihydroxy-17-phenyl-18,19,20-trinor-17-oxaprostane-1-oic acid BDBM50085909 SCHEMBL2305932
Inchi Key	CCIGYTQGGWYUNA-LELZANKISA-N
Inchi ID	InChI=1S/C22H34O6/c23-16(15-28-17-8-4-3-5-9-17)12-13-19-18(20(24)14-21(19)25)10-6-1-2-7-11-22(26)27/h3-5,8-9,16,18-21,23-25H,1-2,6-7,10-15H2,(H,26,27)/t16-,18-,19-,20+,21-/m1/s1
PubChem CID	15486805
ChEMBL	CHEMBL425681
IUPHAR	N/A
BindingDB	50085909
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
38591	Prostacyclin receptor	P43119	PTGIR	Homo sapiens (Human)	386
38595	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
38593	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
38592	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
38597	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
38594	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
38596	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
38590	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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