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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1099112
Molecular formula	C17H11ClN2
IUPAC name	5-chloro-2-(2-methylquinolin-7-yl)benzonitrile
Molecular weight	278.739
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.6
Synonyms	5-Chloro-2-(2-methylquinolin-7-yl)benzonitrile BDBM50317848 D0YZ8G
Inchi Key	BYFVDRQULSVRKZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H11ClN2/c1-11-2-3-12-4-5-13(9-17(12)20-11)16-7-6-15(18)8-14(16)10-19/h2-9H,1H3
PubChem CID	46888044
ChEMBL	CHEMBL1099112
IUPHAR	N/A
BindingDB	50317848
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
35748	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
35749	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
35747	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
35746	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
35745	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
35744	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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