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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL418462
Molecular formula	C13H15ClN2O4
IUPAC name	(2R,4R)-4-amino-1-[(2-chlorophenyl)methyl]pyrrolidine-2,4-dicarboxylic acid
Molecular weight	298.723
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.9
Synonyms	BDBM50071165 SCHEMBL8973329 (2R,4R)-4-Amino-1-(2-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid
Inchi Key	BXTHDFVMVOKYQK-ZWNOBZJWSA-N
Inchi ID	InChI=1S/C13H15ClN2O4/c14-9-4-2-1-3-8(9)6-16-7-13(15,12(19)20)5-10(16)11(17)18/h1-4,10H,5-7,15H2,(H,17,18)(H,19,20)/t10-,13-/m1/s1
PubChem CID	44302819
ChEMBL	CHEMBL418462
IUPHAR	N/A
BindingDB	50071165
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
35425	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
35426	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
35423	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
35427	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
35428	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
35424	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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