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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LY 395756
Molecular formula	C9H13NO4
IUPAC name	(1S,2S,4R,5R,6S)-2-amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	199.206
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	-2.8
Synonyms	AKOS025295798 ZINC13644423 CHEMBL192051 (1S,2S,4R,5R,6S)-2-Amino-4-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid LY-541850 BDBM50167032 CTK8E6819 RT-013617 [ Show all ]
Inchi Key	BQVZICWQBFTOJX-QNDZYWSYSA-N
Inchi ID	InChI=1S/C9H13NO4/c1-3-2-9(10,8(13)14)6-4(3)5(6)7(11)12/h3-6H,2,10H2,1H3,(H,11,12)(H,13,14)/t3-,4+,5+,6+,9+/m1/s1
PubChem CID	11310142
ChEMBL	CHEMBL192051
IUPHAR	N/A
BindingDB	50167032
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30715	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
30713	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
30714	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
30712	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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