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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2153560
Molecular formula	C20H25NO6
IUPAC name	2-(2,6-dimethoxyphenoxy)-N-[[(2R)-5-methoxy-2,3-dihydro-1,4-benzodioxin-2-yl]methyl]ethanamine
Molecular weight	375.421
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	2.9
Synonyms	BDBM50392648 (R)-N-[2-(2,6-Dimethoxyphenoxy)ethyl]-5-methoxy-2,3-dihydro-1,4-benzodioxin-2alpha-methanamine CHEMBL2220899
Inchi Key	BPBCIZXGJQIHRC-CQSZACIVSA-N
Inchi ID	InChI=1S/C20H25NO6/c1-22-15-6-4-7-16(23-2)19(15)25-11-10-21-12-14-13-26-20-17(24-3)8-5-9-18(20)27-14/h4-9,14,21H,10-13H2,1-3H3/t14-/m1/s1
PubChem CID	10764133
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50392648
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29371	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
29373	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
29374	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
29372	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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