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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1935426
Molecular formula	C23H33NO4S
IUPAC name	4-[(1'-cyclobutylspiro[3,4-dihydrochromene-2,4'-piperidine]-6-yl)oxymethyl]thiane 1,1-dioxide
Molecular weight	419.58
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.7
Synonyms	BDBM50360974 SCHEMBL12749182
Inchi Key	BITWXVYTBYRISR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H33NO4S/c25-29(26)14-7-18(8-15-29)17-27-21-4-5-22-19(16-21)6-9-23(28-22)10-12-24(13-11-23)20-2-1-3-20/h4-5,16,18,20H,1-3,6-15,17H2
PubChem CID	56835087
ChEMBL	CHEMBL1935426
IUPHAR	N/A
BindingDB	50360974
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24728	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
24726	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
24725	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
24727	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
24729	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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