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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BDBM50090015
Molecular formula	C27H28F3N5O2
IUPAC name	(6S)-N-[3-[4-(2-cyano-4-fluorophenyl)piperidin-1-yl]propyl]-6-(3,4-difluorophenyl)-4-methyl-2-oxo-5,6-dihydro-1H-pyrimidine-5-carboxamide
Molecular weight	511.549
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.2
Synonyms	4-(3,4-Difluoro-phenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydro-pyrimidine-5-carboxylic acid {3-[4-(2-cyano-4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
Inchi Key	BGUAAEOBBQFCOR-WUBHUQEYSA-N
Inchi ID	InChI=1S/C27H28F3N5O2/c1-16-24(25(34-27(37)33-16)18-3-6-22(29)23(30)14-18)26(36)32-9-2-10-35-11-7-17(8-12-35)21-5-4-20(28)13-19(21)15-31/h3-6,13-14,17,24-25H,2,7-12H2,1H3,(H,32,36)(H,34,37)/t24?,25-/m1/s1
PubChem CID	91931388
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50090015
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23423	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
23421	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
23422	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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